Author

Marcell Zimanyi

University of California, San FranciscoORCID 0000-0003-1981-1244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Charles S. CraikiD· 2 shared Yifan ChengiD· 2 shared Aaron BodanskyiD· 1 shared Andoni I. AsencoriD· 1 shared Cristina Dabaco· 1 shared James AsakiiD· 1 shared John V. PluvinageiD· 1 shared Jordan NormaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Charles S. CraikORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structure-guided design of a targeted autoantibody degrader for neurologic disease

Marcell Zimanyi, Monica T. Dayao, Andoni I. Asencor, Sravani Kondapavulur, James Asaki, Krista M. McCutcheon, Cristina Dabaco, Aaron Bodansky, Charles S. Craik, Samuel J. Pleasure, Joseph L. DeRisi, Yifan Cheng, Michael R. Wilson, John V. Pluvinage

This paper designs a targeted autoantibody degrader to treat neurologic diseases by specifically clearing pathogenic autoantibodies while preserving the immune system.

bioRxiv · Feb 3, 2026 · PreprintNeuroscience

Antibody Reveals Conformational Latch Controlling Herpesvirus Proteases

Marcell Zimanyi, Kaitlin R. Hulce, Markus‐Frederik Bohn, Jordan Norman, Peter J. Rohweder, Yifan Cheng, Charles S. Craik

The paper identifies a conserved loop in herpesvirus proteases that controls dimerization and enzyme activity, presenting a new target for antiviral inhibitors.

bioRxiv · Oct 17, 2025 · PreprintBiochemistry