Author

İbrahim Kulaç

Koç UniversityORCID 0000-0003-2003-7567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ali Cenk AksuiD· 2 shared Altar OzbıyıkiD· 2 shared Ayşe Hümeyra Dur KarasayariD· 2 shared İpek Kok· 2 shared Tugba Bagci OnderiD· 2 shared Adam P. CribbsiD· 1 shared Ahmet CingöziD· 1 shared Alişan KayaböleniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Ali Cenk AksuORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

DDRKOL: A Focused CRISPR Library for Systematic Identification of DNA Damage Response Dependencies in Glioblastoma

Canan Bayraktar, İpek Kok, Altar Ozbıyık, Alişan Kayabölen, Ali Cenk Aksu, Ayşe Hümeyra Dur Karasayar, İlknur Sur‐Erdem, İbrahim Kulaç, Tugba Bagci Onder

DDRKOL identifies essential DDR genes in glioblastoma using CRISPR screens, revealing four high-confidence candidates validated across multiple assays and models.

bioRxiv · Sep 13, 2026 · PreprintCancer Biology

Glio-SERS: Label-Free Molecular Profiling of Plasma Extracellular Vesicles in Brain Tumors Using SERS and Artificial Intelligence

Hülya Torun, Uğur Parlatan, Tim Valencony, Demir Akin, Chris Nguyen, Özgür Albayrak, Furkan Kaysin, Uğur Aygün, Bharti Singal, Mehmet Ozgün Ozen, Rana Cansu Egitimci, İbrahim Kulaç, Oğuz Baran, Göktuğ Akyoldaş, İhsan Solaroğlu, Utkan Demirci

This study develops Glio-SERS, a method combining SERS and AI to profile plasma extracellular vesicles in brain tumors, showing 88% accuracy in distinguishing glioblastoma and meningioma from healthy controls.

bioRxiv · Apr 23, 2026 · PreprintBioengineering

Functional Genomic Screens Reveal RBBP4 as a Key Regulator of Cell Cycle Progression in TMZ-Resistant Glioblastoma

Ezgi Yağmur Kala, Filiz Senbabaoglu Aksu, Muhammed Erdem Ercan, Altar Ozbıyık, Ahmet Cingöz, Ozlem Yedier-Bayram, Ali Cenk Aksu, Ayşe Derya Cavga, Ebru Yilmaz, İpek Kok, Ayşe Hümeyra Dur Karasayar, İbrahim Kulaç, Hamzah Syed, Martin Philpott, Adam P. Cribbs, Tugba Bagci Onder

This study identifies RBBP4 as a critical regulator of cell cycle progression in TMZ-resistant glioblastoma through CRISPR screens and functional analyses.

bioRxiv · May 9, 2025 · PreprintCancer Biology