Marko Kaksonen

The paper identifies Ldb17 as the on-switch for endocytic actin assembly in S. cerevisiae, revealing its complex regulation by Sla1 and evolutionary divergence from Dip1 in S. pombe.

This study shows that Pan1 self-assembles into condensates during clathrin-mediated endocytosis in budding yeast, driven by adaptor interactions and regulated by specific protein domains.

The paper shows that clathrin turnover switches during endocytosis, affecting coat size and organization in yeast.

This study shows HRS forms 2D condensates that drive flat clathrin lattice assembly on endosomes, with cholesterol enhancing this process.

This study investigates how tricalbin domains regulate membrane contact site organization in yeast through lipid binding and curvature sensing.

This study identifies an ancient membrane fission mechanism in Asgard archaea, showing ESCRT-III's role in cell compartmentalization predates eukaryogenesis.

The paper maps the actin fusion focus in S. pombe with 8 nm precision, showing myosin V transports formin Fus1 for actin aster compaction.

This study uses dikarya fungi to investigate evolutionary differences in clathrin-mediated endocytosis, revealing phenotypic variations and their implications for mechanistic understanding.

PyF2F measures fluorophore-to-fluorophore distances from PICT data, validated on a published dataset.