James J. Gilchrist

The paper identifies four genome-wide significant loci affecting monocyte cytokine release and links genetic variants to cytokine secretion patterns.

The paper identifies African-specific genetic loci associated with iron status and risk of severe malaria and bacteremia in children, highlighting limited transferability of European polygenic risk scores.

The paper identifies genetic determinants of CD8+ T cell receptor (TCR) repertoire in cancer patients before and after immune checkpoint blockade (ICB) treatment, finding associations with HLA alleles and treatment response.

The paper characterizes genetic determinants of context-specific DNA methylation in primary monocytes exposed to inflammatory stimuli, identifying 209 CpGs under genetic control and linking them to disease.

The paper identifies eQTL specific to NK cells and links them to autoimmunity through transcriptome-wide association studies.