Matteo Mazzocca

This study shows that SAF-A/HNRNPU regulates euchromatin dynamics and is essential for maintaining nuclear envelope integrity through transcription-dependent mechanisms.

The paper tracks chromatin dynamics across seven orders of magnitude in human and mouse cells, finding strongly subdiffusive behavior with limited sensitivity to transcription and histone modifications.

This study investigates how NF-κB co-activation enhances p53 accumulation dynamics, impairing DNA repair and revealing a transcriptionally mediated antagonism between p53 and NF-κB.

This study shows MYC enhances TOP2A diffusion, promoting its substrate binding and chromatin engagement, thereby stimulating topoisomerase activity.