Christian H. Gabriel

This paper introduces a lentiviral fluorescent reporter for studying circadian rhythms in single cells, enabling the measurement of circadian dynamics parameters like phase and period.

The paper investigates how circadian period compensates for fluctuations in repressor protein turnover rates in single cells using fluorescently labeled proteins and mathematical modeling.

The paper defines and analyzes two types of amplitude-period correlations in circadian rhythms and shows their impact on oscillator-environment interactions.

This study uses a Smg6 mouse model to show that NMD pathway downregulation affects circadian period length and daily CRY2 mRNA accumulation.