Adam C. Abraham

This study shows that the postnatal tendon enthesis remains hypoxic and requires Hif1a for cell survival, ECM organization, and structural integrity.

This study uses photo-crosslinking to induce early fibrotic changes in ex vivo tissue, showing how matrix stiffening affects cell behavior and fibrosis progression.

This study shows that high-viscosity hydrogels lead to increased nascent extracellular matrix deposition by cells, independent of intracellular contractility.

This study examines how puberty suppression and testosterone affect Achilles tendon and enthesis properties in a mouse model of transmasculine gender-affirming hormone therapy, finding improved load capacity and increased cell density with GnRHa treatment.

This study identifies Als4112 as critical for Candida auris skin colonization and explores collagen coatings to prevent adherence.

This study shows AMPK1 is essential for tendon health, preventing senescence and calcification through metabolic regulation and ECM remodeling.

This study shows that overexpressing ChR2-EYFP in skeletal muscle causes contractile dysfunction, while ChR2-only mice show normal function, highlighting the need for alternative optogenetic models.

This study investigates the role of TGFβ signaling in Gli1+ cells during tendon and enthesis development, finding that it regulates proliferation, differentiation, and scleraxis expression.