Mengling Zhang

This study shows Lamin A/C regulates DNA replication by controlling chromatin accessibility and PCNA recruitment, preventing excessive replication initiation and DNA damage.

This paper introduces a new class of fluorophores with enhanced photostability, solubility, and tunable properties for advanced biological imaging applications.

This study uses super-resolution imaging to show that replication origins are preferentially fired at the periphery of TADs due to chromatin re-organization linked to transcription and CTCF.