Author
University of California San DiegoORCID 0000-0003-2212-6803Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Júlia Borges Paes Lemes, Kauê Franco Malange, Alisa Panichkina…·Tony L. Yaksh
This study shows that TLR-4 enhances TRPV1-mediated calcium influx in DRG neurons through PKA signaling, contributing to pain hypersensitivity.
Sara Anna Dochnal, Yixing Du, Daniella Bandari…·Tony L. Yaksh
The paper develops a human-derived in vitro model of nociceptive signaling using HD10.6 cells to study pain mechanisms and drug responses.
Kauê Franco Malange, Douglas Menezes de Souza, Júlia Borges Paes Lemes…·Carlos Amílcar Parada
This study validates an adapted electronic von Frey (aVF) device for measuring joint pain in rats and assesses its response to analgesics in osteoarthritis models.
Kauê Franco Malange, Júlia Borges Paes Lemes, Briana Noble…·Tony L. Yaksh
This study evaluates the analgesic effects of intrathecal NaV 1.7 antisense oligonucleotides in rats, showing reduced channel binding and pain behaviors with concentration-dependent knock-down of Scn9a mRNA.