Yury I. Miller

This paper shows that AAV2-hAIBP preserves retinal ganglion cells and visual function in glaucoma without lowering intraocular pressure by targeting neuroinflammation through the AIBP-TLR4 axis.

This study shows that microglial cholesterol accumulation worsens neuronal synaptic vulnerability to amyloid-beta in Alzheimer's disease.

This study shows that TLR-4 enhances TRPV1-mediated calcium influx in DRG neurons through PKA signaling, contributing to pain hypersensitivity.

This study shows that AIBP deficiency in mice leads to increased foam cell inflammation and atherosclerosis through enhanced inflammaraft expression and lipid accumulation.

The paper develops a human-derived in vitro model of nociceptive signaling using HD10.6 cells to study pain mechanisms and drug responses.

The paper examines AIBP expression in Alzheimer's disease by analyzing human brain tissue and mouse models, finding a progressive loss of astrocytic AIBP with disease progression.

This study shows that restoring AIBP expression in glaucomatous retinas protects retinal ganglion cells and reduces neuroinflammation in mouse models.

This study shows that AIBP regulates TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease, reducing neuroinflammation and neurodegeneration.