M. Shahid Mukhtar

Protein Stability, Turnover Kinetics, and Abundance Constrain the Scaling of Protein Interaction Networks

The paper identifies how protein stability, turnover, and abundance influence the connectivity of protein-protein interaction networks in yeast.

ANYI: The ANnotated Yeast Interactome

ANYI integrates yeast PPI data with sixteen biophysical and regulatory annotations to enable cross-layer interactome analysis.

Integrative systems biology framework discovers common gene regulatory signatures in multiple mechanistically distinct inflammatory skin diseases

The paper identifies common gene regulatory signatures across multiple inflammatory skin diseases using an integrative systems biology framework and proposes potential drug targets.

Characterization and Preclinical Treatment of Rotational Force-Induced Brain Injury

This study develops a rodent model of rotational head trauma, identifies Cdk5 as a key mediator, and shows its inhibition reduces cognitive and pathological effects.

Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis

The paper constructs a human-SARS-CoV-2 interactome using network biology and multiomics data to identify key targets and regulatory circuits involved in SARS-CoV-2 pathogenesis.