Author
Nicole A. Traphagen
Harvard UniversityORCID 0000-0003-2223-5022Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 31 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
Lack of synergy between AR targeted therapies and PARP inhibitors in homologous recombination-proficient prostate cancer
Nicole A. Traphagen, Esmé Wheeler, Rong Li…·Myles A Brown
This study shows that AR inhibition does not enhance PARP inhibitor efficacy in HR-proficient prostate cancer and instead impairs response in castration-sensitive cells.
9 citationstop 1% - Cancer BiologybioRxivPreprint
Super-resolution microscopy reveals distinct epigenetic states regulated by estrogen receptor activity
Tara K. Akhshi, Shengen Shawn Hu, Esmé Wheeler…·Myles A Brown
The paper uses super-resolution microscopy to show that estrogen receptor activity regulates distinct chromatin structures marked by H3K27ac, revealing dynamic epigenetic states and their implications for transcriptional activity and cancer resistance.