Author

Amy Grayson

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

M KellisiD· 2 shared Bingqiu XiuiD· 1 shared Chuqian LiangiD· 1 shared Elio AdibiD· 1 shared Euijung RyuiD· 1 shared G. Kenneth GrayiD· 1 shared Genevra M. KuzieliD· 1 shared Gongwei WuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

M KellisORCID

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2 papers

Recent·Most cited

Circadian misalignment underlies immune escape in breast cancer

Chuqian Liang, Zunpeng Liu, Xiaoke Xu, Zhen Xu, Qi Zhang, Tao Zhang, Riley J. Mangan, Bingqiu Xiu, Gongwei Wu, Tara K. Akhshi, Zachary M. Sandusky, G. Kenneth Gray, Na Zhang, Genevra M. Kuziel, Nicole A. Traphagen, , Myles Brown

The paper identifies circadian misalignment between cancer and immune cells in breast tumors as a mechanism of immune evasion and therapeutic resistance.

bioRxiv · May 29, 2026 · PreprintCancer Biology

Genotype-Epigenome-Phenotype Integration Reveals the Contributions of Peripheral Immune Cells to Bipolar Disorder Pathogenesis, Phenotypic Heterogeneity, and Therapy

Lei Hou, Yue Li, Xushen Xiong, Yosuke Tanigawa, Yongjin Park, Samuel W. Lenz, Amy Grayson, Jeong‐Heon Lee, Euijung Ryu, Janet E. Olson, Joanna M. Biernacka, Mark A. Frye, Tamás Ördög, M Kellis

This study integrates genotype, epigenome, and phenotype data to show immune cells contribute to bipolar disorder pathogenesis, heterogeneity, and therapy through epigenomic and genetic mechanisms.

medRxiv · Mar 17, 2025 · PreprintGenetic & Genomic Medicine