William A. Weiss

The paper identifies six distinct tumor microenvironment niches in glioblastoma that correlate with patient survival and immunotherapy response.

NOVA is an R-package for analyzing MEA data, offering dimensionality reduction, clustering, and trajectory mapping, revealing network burst duration as a key activity metric.

This paper identifies how PVT1 rearrangements in MYC+ cancers generate oncogenic peptides that synergistically activate MYC, AKT, and RAS-MAPK pathways, enhancing tumor aggressiveness.

This study uses in vivo perturb-seq to analyze gene function and radiotherapy responses in glioblastoma by targeting cancer and microenvironment cells.