Author

Joanna Pak

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

David Ronan RaleighiD· 2 shared Harish N. VasudevaniD· 2 shared Kanish MirchiaiD· 2 shared Kyounghee Seo· 2 shared Mitchel Stuart BergeriD· 2 shared Sixuan PaniD· 2 shared Siyuan John LiuiD· 2 shared Tomoko OzawaiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenomics

David Ronan RaleighORCID

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Author profile →

3 papers

Recent·Most cited

Interferon signaling underlies radiotherapy responses in malignant peripheral nerve sheath tumors (MPNSTs)

Iowis Zhu, Julian Chien, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steven E. Braunstein, Line G Jacques, Melike Pekmezci, S. John Liu, Harish N. Vasudevan

This study identifies interferon signaling as a key mediator of radiotherapy response in MPNSTs, linking it to T-cell recruitment and clinical outcomes.

International Journal of Radiation Oncology*Biology*Physics · Sep 1, 2025Peer-reviewedCancer Biology

In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma

Siyuan John Liu, Christopher Zou, Joanna Pak, A. P. Morse, Dillon Pang, Timothy Casey-Clyde, Ashir A. Borah, David Wu, Kyounghee Seo, Thomas O’Loughlin, Daniel A. Lim, Tomoko Ozawa, Mitchel Stuart Berger, Roarke A. Kamber, William A. Weiss, , Luke A. Gilbert

This study uses in vivo perturb-seq to analyze gene function and radiotherapy responses in glioblastoma by targeting cancer and microenvironment cells.

Genome biology · Oct 7, 2024Peer-reviewedGenomics

Multiplatform molecular profiling and functional genomic screens identify prognostic signatures and mechanisms underlying MEK inhibitor response in somatic NF1 mutant glioblastoma

Sixuan Pan, Kanish Mirchia, Emily Payne, Siyuan John Liu, Nadeem N. Al-Adli, Zain Peeran, Poojan D. Shukla, Jacob S. Young, Rohit K. Gupta, Jasper Wu, Joanna Pak, Kyounghee Seo, Tomoko Ozawa, Brian S Na, Alyssa Terry Reddy, , Harish N. Vasudevan

bioRxiv · Jul 1, 2024 · PreprintGenomics