NeuroscienceBiological PsychiatryPeer-reviewed
Low-dose Perampanel rescues cortical gamma dysregulation associated with parvalbumin interneuron GluA2 upregulation in epileptic Syngap1+/- mice
Brennan J. Sullivan, Simon Gashaw Ammanuel, Pavel A. Kipnis…·Shilpa D. Kadam
The paper identifies GluA2 upregulation in parvalbumin interneurons as a cause of gamma dysregulation in Syngap1+/- mice and shows that Perampanel rescues this dysfunction.
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