Author

Anne P. Werner

Johns Hopkins UniversityORCID 0000-0003-2322-6830Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew S PekosziD· 4 shared Elgin Henry AkiniD· 3 shared Katherine FenstermacheriD· 2 shared Lynda CoughlaniD· 2 shared Matthew PinsleyiD· 2 shared Richard Eric RothmaniD· 2 shared Sattya Narayan TalukdariD· 2 shared Amary FalliD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersImmunology

Andrew S PekoszORCID

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4 papers

Recent·Most cited

Sex differences in vaccine-induced neuraminidase cross-recognition impact H5N1 dissemination to the lower respiratory tract in mice

Sabal Chaulagain, Anne P. Werner, Maclaine A. Parish, Sattya Narayan Talukdar, Anna Yin, Brittany Seibert, Tianle Zhang, Jennifer A. Liu, Cosette Schneider, Lynda Coughlan, Andrew S Pekosz, Sabra L. Klein

This study shows that sex differences in vaccine-induced neuraminidase (NA) antibody responses affect H5N1 virus dissemination in mice, with females showing better protection against lower respiratory tract infection.

Vaccine · Sep 27, 2026Peer-reviewedImmunology

Influenza A virus H5N1 genotypes B3.13 and D1.1 show temperature-dependent restriction of replication in primary human respiratory epithelial cell cultures derived from the upper and lower respiratory tract.

Anne P. Werner, Jaiprasath Sachithanandham, Elgin Henry Akin, Sattya Narayan Talukdar, Matthew Pinsley, Andrew S Pekosz

This study compares the temperature-dependent replication of H5N1 genotypes B3.13 and D1.1 with H1N1pdm09 in human respiratory epithelial cells, finding differences in replication efficiency at different temperatures.

bioRxiv · Aug 29, 2026 · PreprintMicrobiology

Emergence of an Antigenically Drifted and Reassorted Influenza B Virus at the end of the 2024-25 Influenza Season

Elgin Henry Akin, David A. Villafuerte, Anne P. Werner, Matthew Pinsley, Corinne Pierce, Amary Fall, Omar Riyadh Abdullah, Julie M. Norton, Richard Eric Rothman, Katherine Fenstermacher, Yu‐Nong Gong, Eili Y. Klein, Heba H. Mostafa, Andrew S Pekosz

This study identifies an antigenically drifted and reassorted Influenza B virus, C.3.1/re, emerging late in the 2024-25 season, which is poorly neutralized by existing vaccines and may impact future vaccine strain selection.

mBio · Jun 22, 2026Peer-reviewedMicrobiology

Low levels of H5N1 HA and NA antibodies in the human population are boosted by seasonal A/H1N1 infection but not by A/H3N2 infection or influenza vaccination

Anne P. Werner, Cosette G. Schneider, Elgin Henry Akin, Juliahna Hayes, Katherine Fenstermacher, Richard Eric Rothman, Lynda Coughlan, Andrew S Pekosz

The paper measures antibody responses to bovine A/H5N1 HA and NA in vaccinated and infected individuals, finding that A/H1N1 infection boosts neutralizing antibodies but vaccination and A/H3N2 infection do not.

mBio · Oct 31, 2025Peer-reviewedImmunology