Swetha E. Murthy

This study shows that PIEZO1 and PIEZO2 channels in oligodendrocytes regulate sheath formation, expansion, and myelination by detecting mechanical cues.

The paper evaluates the Vglut3-IRES-Cre mouse line for identifying non-PIEZO2 mechanosensors in C-LTMRs, finding it labels these neurons but fails to efficiently delete genes like Tmem63b.

This study identifies TMEM63A as a critical regulator of myelination in the CNS, showing its role in oligodendrocyte function and linking its dysfunction to hypomyelinating leukodystrophies.

This study identifies Acj6 as a transcription factor that controls dendrite targeting in Drosophila PNs by regulating combinatorial expression of cell-surface proteins.

This study identifies heterozygous TMEM63A variants causing transient hypomyelination in infancy, with clinical improvement over time.