Glycan-coated nanoparticles mimicking the ischemic glycocalyx scavenge the complement system conferring protection after experimental ischemic stroke
Gizem Erol, Serena Seminara, Domenico Mercurio…·Stefano Fumagalli
The paper demonstrates that glycan-coated nanoparticles can sequester complement lectin pathway components, reducing ischemic brain injury in a mouse model.