Venkatesh N. Murthy

This study investigates generalization versus memorization in mice using an olfactory categorization task, finding that mice prefer generalization over memorization.

The paper shows that mice can discriminate odors in complex mixtures primarily limited by neural sensitivity rather than background complexity.

This study investigates how mice perceive intermittent odor stimuli by analyzing behavioral responses and neural activity in the anterior piriform cortex, finding that respiratory phase modulates perception but limits information acquisition.

This study shows that efficient coding recovers canonical olfactory features by maximizing mutual information layer-wise under biophysical assumptions.

This paper introduces a model for olfactory compressed sensing that simultaneously detects odor presence and estimates concentrations, showing it can be implemented in a biologically plausible circuit.

This study investigates synaptic connectivity development in the mouse cerebellum, revealing sequential input-dependent wiring and individualized parallel fiber inputs to Purkinje cells.

This paper develops a machine learning framework for shaping animal behavior using adaptive algorithms that alternate between simpler and harder tasks to optimize learning.

This study shows mice use predictive policies to navigate scent trails by integrating bilateral olfactory input and short-term memory.

This paper introduces an interpretable deep learning method for deconvolving neural signals, demonstrating its application in analyzing brain activity across different regions and recording modalities.

The paper shows that odor responses in the olfactory cortex of mice are highly matched between hemispheres, allowing decoding of odor identity and laterality through Hebbian plasticity.

The paper investigates how feedforward and feedback inputs to the olfactory bulb encode odor information, finding that feedback provides sparse, decorrelated representations of complex odors.

This study investigates how dopamine signals in the ventral striatum relate to contingency during associative learning in mice, finding that TD learning models with ITI state representations explain the results better than contingency-based models.

This paper proposes a rate-based Poisson compressed sensing model for the olfactory bulb that accurately detects odors within a single sniff.

This study shows how mice's piriform cortex neurons adapt to learn and distinguish odor mixtures, becoming more selective over time and improving population-level categorization.

The paper shows that D1 and D2 neurons in the olfactory tubercle represent odor valence differently, with D1 neurons encoding valence broadly and D2 neurons encoding odor identity more specifically.

This paper shows how natural gradient methods can enable fast sampling in spiking neural networks by leveraging population geometry for probabilistic inference.

The paper shows that antagonistic interactions between odors are common in olfactory sensory neurons of freely breathing mice, helping to normalize activity and reduce saturation in complex odor mixtures.

This study shows that microglia are necessary for the functional development of adult-born neurons in the olfactory bulb by promoting excitatory synapse formation.

The paper identifies a cortico-thalamic circuit in mice that supports social hierarchy through molecular and biophysical plasticity.

This study shows that the olfactory tubercle, not the posterior piriform cortex, rapidly encodes reward category during odor-reward learning, preceding motor actions.

The paper examines how odor features are represented in the input and output layers of the mouse olfactory bulb, finding that physical-chemical descriptors poorly predict neuronal representations.

This study uses 2-photon imaging to show that neuronal integration in the adult olfactory bulb occurs without cell loss and without a critical period, challenging the turnover model.

This study shows that OMP deletion leads to functional and anatomical heterogeneity in olfactory glomeruli due to anomalous co-innervation by OSNs with different ORs.

This study shows that Ano2 clamps odor-evoked spike activity in olfactory receptor neurons in vivo, despite reduced transduction currents in Ano2-/- mice.

The paper models how mammalian olfactory receptor neurons process odor mixtures, showing antagonistic interactions lead to normalization of glomerular responses and improve odor discrimination.

The paper shows that embryonic and postnatal neurogenesis in the olfactory bulb produce functionally distinct subclasses of dopaminergic neurons.

The paper examines the projection patterns of SL and SP neurons in the APC, revealing distinct axonal connections to downstream structures and a hierarchical feedback circuit.