This study identifies genetic variants associated with self-reported childhood maltreatment and finds significant genetic correlations with depressive symptoms.

Translational Psychiatry · Jan 27, 2020Peer-reviewedGenomics

PTSD Biomarker Database: Deep Dive Meta-database for PTSD Biomarkers, Visualizations, and Analysis Tools

Daniel Domingo‐Fernándéz, Allison C. Provost, Alpha Tom Kodamullil, Josep Marín-Llaó, Heather C. Lasseter, Kristophe Diaz, Nikolaos P. Daskalakis, Lee Lancashire, Martin Hofmann‐Apitius, Magali Haas

The PTSD Biomarker Database compiles over 900 PTSD biomarkers from 109 studies to enable exploration and comparison of biomarker findings through interactive visualizations.

Database · Jan 1, 2019Peer-reviewedBioinformatics

Olfactory marker protein regulates refinement of the glomerular map

Dinu Florin Albeanu, Allison C. Provost, Prateek Agarwal, Edward R. Soucy, Joseph D. Zak, Venkatesh N. Murthy

This study shows that OMP deletion leads to functional and anatomical heterogeneity in olfactory glomeruli due to anomalous co-innervation by OSNs with different ORs.

Nature Communications · Nov 23, 2018Peer-reviewedNeuroscience

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia‐Yen Chen, Karmel W. Choi, Jonathan R. I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Mark W. Logue, Allison C. Provost, Andrew D. Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, , Douglas Maurer

This study conducts the largest GWAS for PTSD, identifying 6 genome-wide significant loci in European and African ancestries and highlighting novel biological pathways.

bioRxiv · Nov 1, 2018 · PreprintGenetics