Dennis Wylie

The paper uses deep mutational scanning to study the TRPM8 channel's pore region, revealing how structural elements coordinate gating and ion selectivity in response to menthol and cold.

This study shows that postnatal maternal care reduces DNA methylation changes in the hypothalamus caused by prenatal bisphenol exposure in female rats.

The paper examines transcriptomic correlations between brain and blood in depressive disorders and comorbid psychopathologies, finding concordant and discordant gene expression patterns across tissues.

This study identifies widespread linear molecular mimicry across the human virome, linking it to autoimmunity, particularly in multiple sclerosis, and suggests therapeutic strategies targeting viral infections.

This study uses TGIRT-seq to analyze IBC tumor and blood samples, revealing widespread transcriptional changes and RNA splicing impacts in plasma.

SArKS identifies cell type-specific DNA regulatory sequences by smoothing differential expression scores over sequence and spatial similarity, outperforming existing methods in motif discovery.