NeuroscienceNeuroscience LettersPeer-reviewed
Post-weaning social isolation increases ΔFosB/FosB protein expression in the prefrontal cortex and hippocampus in mice
Michael N. Noback, Gongliang Zhang, Noelle White…·Gregory V. Carr
12 citations
Author
Johns Hopkins UniversityORCID 0000-0003-2559-4282Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Michael N. Noback, Gongliang Zhang, Noelle White…·Gregory V. Carr
Spencer Byers, Ingrid P. Buchler, Michael J. Depasquale…·Gregory V. Carr
The paper identifies novel COMT inhibitors that improve cognitive flexibility in rats by modulating dopamine metabolites in the frontal cortex and cerebrospinal fluid.
Gongliang Zhang, Ingrid P. Buchler, Michael J. Depasquale…·Gregory V. Carr
This study evaluates the use of PC12 cells as an in vitro platform to screen COMT inhibitors, showing that tolcapone and LIBD-3 increase dopamine and DOPAC while reducing 3-MT and HVA.