Author

Ingrid P. Buchler

Lieber Institute for Brain Development

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:rat· 3 Organism:mouse· 1

Frequent Co-Authors

Gregory V. CarriD· 3 shared James C. BarrowiD· 3 shared Gongliang ZhangiD· 2 shared Huijun WeiiD· 2 shared Michael J. Depasquale· 2 shared Adrienne C. DeBrosse· 1 shared Anna Kolobova· 1 shared Brady J. MaheriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Gregory V. CarrORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Development of a Novel Benzodiazepine to Delineate Peripheral GABA-A Signaling Mechanisms in Visceral Pain Syndromes

Michael S. Poslusney, Qian Li, Ingrid P. Buchler, Yifang Huang, Liansheng Liu, Yaohui Zhu, Subhash Kulkarni, Gregory V. Carr, Adrienne C. DeBrosse, Noelle White, Diane E. Peters, James C. Barrow, Pankaj Jay Pasricha

This study develops a novel benzodiazepine, Li633, that targets peripheral GABAA receptors to reduce visceral pain in IBS and FD models.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2026Peer-reviewedNeuroscience

Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins Syndrome

Joseph F. Bohlen, Colin M. Cleary, Debamitra Das, Srinidhi Rao Sripathy, Norah Sadowski, Gina Shim, Rakaia F. Kenney, Ingrid P. Buchler, Daniel Kent Mulkey, Brady J. Maher

bioRxiv · May 3, 2022 · PreprintNeuroscience

Novel, non-nitrocatechol COMT inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

Spencer Byers, Ingrid P. Buchler, Michael J. Depasquale, Helen L. Rowley, Rajiv S. Kulkarni, Lucy Pinder, Anna Kolobova, Cailian Li, Vinh Au, Daniel Akuma, Gongliang Zhang, Huijun Wei, Sharon C. Cheetham, James C. Barrow, Gregory V. Carr

The paper identifies novel COMT inhibitors that improve cognitive flexibility in rats by modulating dopamine metabolites in the frontal cortex and cerebrospinal fluid.

Psychopharmacology · May 30, 2020Peer-reviewedNeuroscience

Development of a PC12 cell-based assay for in vitro screening of catechol-O-methyltransferase inhibitors

Gongliang Zhang, Ingrid P. Buchler, Michael J. Depasquale, Michael Wormald, Gangling Liao, Huijun Wei, James C. Barrow, Gregory V. Carr

This study evaluates the use of PC12 cells as an in vitro platform to screen COMT inhibitors, showing that tolcapone and LIBD-3 increase dopamine and DOPAC while reducing 3-MT and HVA.

ACS Chemical Neuroscience · Sep 6, 2019Peer-reviewedNeuroscience