Michael Wagner

This paper introduces an automated method to quantify white matter hyperintensity confluence, showing it correlates with cognitive performance and dementia subtypes beyond volume.

This study examines how episodic memory network dysfunction relates to AD biomarkers, neurodegeneration, and cognition using longitudinal fMRI data from the DZNE study.

The paper links cognitive reserve to brain activity during memory formation, showing it moderates the impact of Alzheimer's pathology on cognitive performance and predicts slower decline.

This study shows that PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease-related markers in neurons.

The paper examines if fractional anisotropy of the fornix mediates the link between Mediterranean diet adherence and verbal memory decline in older adults over four years.

The paper identifies diagnostic images that correlate with Alzheimer's biomarkers and show differential neural processing in MCI patients compared to healthy controls.

The paper identifies high-priority missense variants in SORL1 associated with increased Alzheimer's Disease risk and earlier onset, suggesting clinical counseling considerations for carriers.

The paper identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimer's Disease using exome sequencing data from 32,558 individuals.

This study finds that lifelong musical activity is linked to better cognitive abilities and preserved brain structure in older adults, suggesting it may enhance cognitive resilience.

The paper uses Gaussian process multikernel modeling to predict memory performance and CSF biomarkers in ageing and Alzheimer's disease using MRI and other data.

This study identifies a genome-wide significant variant for OC traits and shows shared genetic risk between OC traits and OCD.

This study identifies gene sets associated with Tourette Syndrome using genome-wide data, highlighting synaptic and immune-related pathways.

The paper assesses memorability of photographs in healthy controls, subjective cognitive decline, and mild cognitive impairment, identifying images with diagnostic potential.

The paper identifies OCD-associated genes by combining evolutionary and functional data with targeted sequencing in humans and animal models.