Author

Ao Guo

Peking UniversityORCID 0000-0003-2597-7558Unclaimed ORCID profile · follow to get notified of new preprints

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Ao Guo1 paper · Zhejiang University

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ashutosh MishraiD· 1 shared Dalia HaydariD· 1 shared Douglas R. GreeniD· 1 shared Emilio Boada-RomeroiD· 1 shared Evan Scott GlazeriD· 1 shared Giedre KrenciuteiD· 1 shared Gustavo PalaciosiD· 1 shared Jinan CheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Ashutosh MishraORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 20, 2026

Selective activation of IRE-1 safeguards restoration of translation and organismal rejuvenation from adult reproductive diapause

Qiang Fan, Ao Guo, 王淑娟…·Meng‐Qiu Dong

This study shows that refeeding reverses aging-like phenotypes in C. elegans reproductive diapause by selectively activating the IRE-1 branch of UPRER and enhancing protein synthesis and folding.

DOI 10.64898/2026.03.18.712261

C. elegansproteomics

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ImmunologyNature ImmunologyPeer-reviewedJul 23, 2025

An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.

Piyush Sharma, Ao Guo, Suresh Poudel…·Douglas R. Green

The paper shows that early arginine methylation of KCa3.1 limits Ca2+-mediated NFAT1 activation, preventing T cell exhaustion during activation.

45 citationstop 1%

mouseproteomics

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