Author

Qiang Fan

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cell Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Rashika Joshi· 2 shared Andrea Heinz· 1 shared Andrew J. Devine· 1 shared Ansley N. Varisco· 1 shared Anthony S. Weiss· 1 shared Ao GuoiD· 1 shared Basilia ZingarelliiD· 1 shared Brandon Brooks-Patton· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPathology

Rashika Joshi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selective activation of IRE-1 safeguards restoration of translation and organismal rejuvenation from adult reproductive diapause

Qiang Fan, Ao Guo, 王淑娟, Wuling Yang, Yong-Hong Yan, Meng‐Qiu Dong

This study shows that refeeding reverses aging-like phenotypes in C. elegans reproductive diapause by selectively activating the IRE-1 branch of UPRER and enhancing protein synthesis and folding.

bioRxiv · Mar 20, 2026 · PreprintCell Biology

KF4 anti-CELA1 Antibody and Purified α1-Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine α1-Antitrypsin Deficiency

Andrew J. Devine, Noah J. Smith, Rashika Joshi, Brandon Brooks-Patton, Jenna Dunham, Ansley N. Varisco, Emily M. Goodman, Qiang Fan, Basilia Zingarelli, Brian M. Varisco

This study evaluates KF4 anti-CELA1 antibody and purified α1-antitrypsin in preventing emphysema in AAT-deficient mice, finding similar efficacy with no additive benefit when combined.

Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation · Nov 26, 2024Peer-reviewedPathology

Role Of Chymotrypsin-Like Elastase 1 In Lung Physiology And in α1-Antitrypsin Deficiency

Rashika Joshi, Andrea Heinz, Qiang Fan, Shuling Guo, Brett Monia, Christian E.H. Schmelzer, Anthony S. Weiss, Matthew Batie, Harikrishnan Parameswaran, Brian M. Varisco

This study shows Cela1 is responsible for stretch-inducible lung elastase activity and is required for emphysema in AAT deficiency, with conserved features in placental mammals.

bioRxiv · May 16, 2017 · PreprintPhysiology