Author

Sébastien Leblanc

Université de SherbrookeORCID 0000-0003-2599-6716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:protein structure prediction· 2 Approach:experimental assay· 1 Assay:metagenomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Marie A. BrunetiD· 3 shared Francis BourassaiD· 2 shared Ihor ArefieviD· 2 shared Xavier RoucouiD· 2 shared Aaron C. WacholderiD· 1 shared Alan Arthur CoheniD· 1 shared Alexia Tremblay· 1 shared Alexis Bruggeman-Gascon· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMolecular Biology

Marie A. BrunetORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 20, 2026

Discovery of non-canonical proteins through modification-aware proteogenomics

Valeriia Vasylieva, Enrico Massignani, Tine Claeys…·Marie A. Brunet

This paper demonstrates that using ionbot with OpenProt improves detection of non-canonical proteins by reducing FDR and increasing reproducibility compared to TPP.

DOI 10.64898/2026.08.17.745157

humanproteomics

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GenomicsbioRxivPreprintFeb 19, 2025

Detection of human unannotated microproteins by mass spectrometry-based proteomics: a community assessment

Aaron C. Wacholder, Eric W. Deutsch, Leron W. Kok…·Anne‐Ruxandra Carvunis

The paper assesses MS-based identifications of unannotated human microproteins, finding large variation in reported proteins and PSM quality across studies.

6 citations

humanproteomics

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Systems BiologyGenomics Proteomics & BioinformaticsPeer-reviewedSep 30, 2022

Newfound coding potential of transcripts unveils missing members of human protein communities

Sébastien Leblanc, Marie A. Brunet, Jean‐François Jacques…·Xavier Roucou

The paper identifies 280 alternative proteins in human protein-protein interaction networks using proteogenomic data and experimental validation, revealing new interactions and functional roles.

12 citations

humanproteomics

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