Enrico Massignani

This paper demonstrates that using ionbot with OpenProt improves detection of non-canonical proteins by reducing FDR and increasing reproducibility compared to TPP.

Scop3P is updated to integrate phosphorylation sites with structural, functional, and mutational data, enhancing phosphosite interpretation and disease context.

MoDPA infers modification-dependent protein associations from reprocessed mass spectrometry data, identifying clusters of modified proteins involved in specific biological pathways.

The paper presents a high-quality human methyl-proteome dataset generated using hmSILAC and a machine learning tool, showing improved identification of methyl-peptides and novel histone methylation marks.

This study identifies PRMT1-mediated methylation of the Large Drosha Complex as critical for miRNA biogenesis by regulating pri-to-pre-miRNA processing.