Author

Ida Hyllen Klæstrup

Aarhus UniversityORCID 0000-0003-2605-3955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Marina Romero‐RamosiD· 4 shared Gitte U. Toft· 2 shared Johanne Lauritsen· 2 shared Line Sinnathamby ReinertiD· 2 shared Poul Henning JenseniD· 2 shared Sara Almeida FerreiraiD· 2 shared Søren R. PaludaniD· 2 shared Yonglun LuoiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersNeuroscience

Marina Romero‐RamosORCID

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4 papers

Recent·Most cited

Neurosciencenpj Parkinson s DiseasePeer-reviewedDec 11, 2025

Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein preformed fibrils Parkinson's Disease mouse model

Ida Hyllen Klæstrup, Line Sinnathamby Reinert, Sara Almeida Ferreira…·Marina Romero‐Ramos

The paper investigates the role of STING in Parkinson's disease by comparing motor behavior and brain pathology in STING-deficient and wild-type mice exposed to alpha-synuclein fibrils.

4 citations

mouseexperimental assay

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ImmunologyJournal of NeuroinflammationPeer-reviewedMay 31, 2025

Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus 1 CNS infection

Xiangning Ding, Xin Lai, Ida Hyllen Klæstrup…·Søren R. Paludan

This study uses single-cell RNA sequencing to analyze the temporal cellular responses in the brain during HSV-1 infection, identifying distinct immune cell subpopulations and their roles in both protective and pathological processes.

17 citationstop 3%

mousescRNA-seq

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Neurosciencenpj Parkinson s DiseasePeer-reviewedDec 13, 2023

Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson's disease

Sara Almeida Ferreira, Conghui Li, Ida Hyllen Klæstrup…·Marina Romero‐Ramos

The paper investigates the sex-dimorphic neuroprotective role of CD163 in a Parkinson's disease mouse model using CD163 knockout mice.

11 citations

mousebulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedDec 5, 2023

Enhanced Production of Mesencephalic Dopaminergic Neurons from Lineage-Restricted Human Undifferentiated Stem Cells

Muyesier Maimaitili, Muwan Chen, Fabia Febbraro…·Mark Denham

This study genetically modifies human pluripotent stem cells to generate lineage-restricted undifferentiated stem cells that efficiently produce mesencephalic dopaminergic neurons for potential clinical applications.

14 citations

humanexperimental assay

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