Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein preformed fibrils Parkinson's Disease mouse model
Ida Hyllen Klæstrup, Line Sinnathamby Reinert, Sara Almeida Ferreira, Johanne Lauritsen, Gitte U. Toft, Hjalte Gram, Poul Henning Jensen, Søren R. Paludan, Marina Romero‐Ramos
The paper investigates the role of STING in Parkinson's disease by comparing motor behavior and brain pathology in STING-deficient and wild-type mice exposed to alpha-synuclein fibrils.
npj Parkinson s Disease · Dec 11, 2025Peer-reviewedNeuroscience