Author
Fox Chase Cancer CenterORCID 0000-0003-2608-0128Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Aasiya Remtulla, Alison Kurimchak, Alicia Canuel…·Michael F. Olson
This study identifies MRCKα as a repressor of GEF-H1-mediated RhoA activation, promoting ovarian cancer spheroid growth and invasion.
Tong Gao, Pingfeng Zhang, Alison Kurimchak…·Jinhua Wu
The paper shows that the short Lpd isoform specifically binds Rac1 via a noncanonical helical interface, revealing a novel isoform-dependent GTPase-effector interaction.
Jason S. Wasserman, Alison Kurimchak, Carlos Herrera-Montávez…·James S. Duncan
The paper identifies a kinase-independent role of MEK1/2 in stabilizing and maturing CRAF through direct binding, independent of catalytic activity.
Jason S. Wasserman, Bulat Faezov, Kishan R. Patel…·Xavier Graña
This paper identifies FAM122A as a SLiM-dependent inhibitor of B55/PP2A that competes with substrates to regulate cell cycle progression and checkpoint control.