Eileen Malko Shore

This study shows that the Acvr1R206H mutation in FOP remodels chromatin through BMP-SMAD and Rho/ROCK signaling, driving aberrant osteogenesis, and identifies reversible chromatin changes as a therapeutic target.

This paper describes an outreach module designed to engage high school students in orthopaedic research, showing significant learning gains and increased interest in the field.

This study investigates how FOP mutant ACVR1 receptors in zebrafish have altered requirements for GS domain phosphorylation and signaling, revealing distinct mechanisms for ligand-dependent and -independent signaling.