Ellen Y. Zhang

This paper develops a biomimetic scaffold system to enhance rotator cuff enthesis regeneration by replicating native tissue properties and integrating with conventional suture anchors.

This study shows that the Acvr1R206H mutation in FOP remodels chromatin through BMP-SMAD and Rho/ROCK signaling, driving aberrant osteogenesis, and identifies reversible chromatin changes as a therapeutic target.

This study identifies chromatin stability as critical for preserving chondrocyte function during expansion and shows that Fludarabine maintains phenotype by stabilizing chromatin and reducing STAT1 activity.

This study identifies age-dependent chromatin remodeling in tendon cells that enhances inflammatory responses and contributes to tendon degeneration.

O-SNAP extracts and classifies chromatin features from SMLM data, detecting subtle changes in chromatin organization across biological transitions.

This paper develops a tunable hydrogel system using decellularized meniscus extracellular matrix to repair zonal-specific meniscal injuries, showing improved cell differentiation and tissue integration.

This study investigates how epigenetic mechanisms regulate meniscus cell migration under inflammation, revealing zonal differences and potential therapeutic targets.