Su‐Jin Heo

This paper develops a biomimetic scaffold system to enhance rotator cuff enthesis regeneration by replicating native tissue properties and integrating with conventional suture anchors.

This study shows that the Acvr1R206H mutation in FOP remodels chromatin through BMP-SMAD and Rho/ROCK signaling, driving aberrant osteogenesis, and identifies reversible chromatin changes as a therapeutic target.

This study identifies chromatin stability as critical for preserving chondrocyte function during expansion and shows that Fludarabine maintains phenotype by stabilizing chromatin and reducing STAT1 activity.

This paper develops a tunable vascular dECM platform to study stiffness-driven vascular remodeling and identifies YAP and survivin as regulators of VSMC mechanotransduction.

This study shows that mechanical loading increases the production and regenerative potential of meniscus cell-derived extracellular vesicles by enriching their cargo with matrix and development-related proteins.

This study identifies age-dependent chromatin remodeling in tendon cells that enhances inflammatory responses and contributes to tendon degeneration.

This study develops a PKPD model integrating in vitro and in vivo data to optimize phage therapy against multidrug-resistant Pseudomonas aeruginosa, showing that phage combinations delay resistance but may lead to immune clearance of resistant mutants.

This study identifies genetic risk factors for meniscus degeneration and shows they are linked to various systemic conditions through a phenome-wide association study.

This study combines theoretical modeling and high-resolution imaging to reveal how chromatin-lamina interactions and environmental cues influence LAD formation and thickness in hMSCs.

O-SNAP extracts and classifies chromatin features from SMLM data, detecting subtle changes in chromatin organization across biological transitions.

The paper evaluates proteomic and polygenic risk scores for disease prediction, finding proteomic scores outperform polygenic scores in most traits and show temporal responsiveness.

This study shows survivin enhances VSMC migration in stiff environments, suggesting it could be a therapeutic target for arterial stiffness-related diseases.

This study investigates the structure-mechanical properties and mechanobiological functions of the pericellular matrix in fibrocartilage, highlighting the critical role of collagen V in maintaining its integrity and function.

This paper develops a tunable hydrogel system using decellularized meniscus extracellular matrix to repair zonal-specific meniscal injuries, showing improved cell differentiation and tissue integration.

This study investigates how epigenetic mechanisms regulate meniscus cell migration under inflammation, revealing zonal differences and potential therapeutic targets.

This study identifies Gli1+ cells as a progenitor population in meniscus development and injury repair, showing their therapeutic potential in preventing osteoarthritis.