Author

Douglas W. Roberts

University of PennsylvaniaORCID 0000-0001-7751-7268Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Bat‐Ider TumenbayariD· 1 shared Eileen Malko ShoreiD· 1 shared Ellen Y. ZhangiD· 1 shared Inkyung JungiD· 1 shared Jaeun Jung· 1 shared Loreilys Mejias RiveraiD· 1 shared Robert L. MauckiD· 1 shared Sang Hyun LeeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Bat‐Ider TumenbayarORCID

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1 paper

Recent·Most cited

BioengineeringJournal of Bone and Mineral ResearchPeer-reviewedJun 5, 2026

Hyperactive BMP and Mechanosignaling Remodel Chromatin to Drive Aberrant Osteogenesis in FOP

Ellen Y. Zhang, Douglas W. Roberts, Sang Hyun Lee…·Su‐Jin Heo

This study shows that the Acvr1R206H mutation in FOP remodels chromatin through BMP-SMAD and Rho/ROCK signaling, driving aberrant osteogenesis, and identifies reversible chromatin changes as a therapeutic target.

DOI 10.1093/jbmr/zjag089

mouseATAC-seq

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