ImmunologyCell ReportsPeer-reviewed
The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization
Andrea Gramatica, Itzayana G. Miller, Adam R. Ward…·R. Brad Jones
The paper shows that tazemetostat reduces HIV reservoirs and improves CD8+ T-cell function by increasing MHC-I expression and promoting anti-HIV immune responses.
20 citationstop 1%