Author

Adam R. Ward

Weill Cornell MedicineORCID 0000-0002-7038-5597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

R. Brad Jones· 2 shared Alberto BosqueiD· 1 shared Ali DaneshiD· 1 shared Andrea GramaticaiD· 1 shared Andrew P. KurlandiD· 1 shared Andrey I. Ivanov· 1 shared Bernard J. C. MacatangayiD· 1 shared Callie Levinger· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

R. Brad Jones

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Author profile →

3 papers

Recent·Most cited

Q4ddPCR (May the Fourth Be Precise): A Flexible, 4-Target Assay for High-Resolution HIV Reservoir Profiling

Rachel Scheck, Mark Melzer, Gregory T. Gladkov, Adam R. Ward, Daniel B. Reeves, Naomi Perkins, T. Thinh Huynh, Deborah K. McMahon, Ronald J. Bosch, Bernard J. C. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Rajesh Tim Gandhi, Lisa Buchauer, , Christian Gaebler

Q4ddPCR improves HIV reservoir quantification by targeting four conserved regions, achieving 95% accuracy and revealing clonal dynamics not detectable by IPDA.

bioRxiv · Jul 28, 2025 · PreprintImmunology

The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization

Andrea Gramatica, Itzayana G. Miller, Adam R. Ward, Khan Farzana, Tyler J. Kemmer, Jared Weiler, Tan Thinh Huynh, Paul Zumbo, Andrew P. Kurland, Louise Leyre, Yanqin Ren, Thaís Klevorn, Dennis C. Copertino, Uchenna K. Chukwukere, Callie Levinger, , R. Brad Jones

The paper shows that tazemetostat reduces HIV reservoirs and improves CD8+ T-cell function by increasing MHC-I expression and promoting anti-HIV immune responses.

Cell Reports · May 1, 2025Peer-reviewedImmunology

Abundance of Nef and p-Tau217 in brains of individuals diagnosed with HIV-associated neurocognitive disorders correlate with disease severance

Tatiana Pushkarsky, Adam R. Ward, Andrey I. Ivanov, Xionghao Lin, Dmitri Sviridov, Sergei A. Nekhai, Michael Bukrinsky

The paper correlates the abundance of Nef and p-Tau217 in brain samples from HIV-infected individuals with HAND severity and lipid raft markers.

Molecular Neurobiology · Nov 29, 2021Peer-reviewedNeuroscience