Author

Garrett J. Brinkley

University of Alabama at BirminghamORCID 0000-0003-2622-3416Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander J. FittiD· 2 shared Hongde LiiD· 2 shared Jason M. TennesseniD· 2 shared Nader H. MahmoudzadehiD· 2 shared Sunil SudarshaniD· 2 shared Angelo D’AlessandroiD· 1 shared Anirban KunduiD· 1 shared Armin P. MoczekiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetics

Alexander J. FittORCID

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2 papers

Recent·Most cited

GeneticsMolecular MetabolismPeer-reviewedAug 23, 2024

Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Nader H. Mahmoudzadeh, Yasaman Heidarian, Jason P. Tourigny…·Jason M. Tennessen

This study shows that L2hgdh in Drosophila renal tubules prevents L-2HG accumulation, supports mitochondrial metabolism, and enables hypoxia tolerance.

5 citations

Drosophilaexperimental assay

𝕏 PostBluesky

Developmental BiologyInsect Biochemistry and Molecular BiologyPeer-reviewedNov 3, 2020

The oncometabolite L-2-hydroxyglutarate is a common product of Dipteran larval development

Nader H. Mahmoudzadeh, Alexander J. Fitt, Daniel B. Schwab…·Jason M. Tennessen

The paper investigates L-2-hydroxyglutarate (L-2HG) accumulation in 18 insect species, finding high levels in Dipterans and suggesting a potential role in their development and pest control.

12 citations

DrosophilaArabidopsis

𝕏 PostBluesky