Éster Cerdeira Sabino

This study identifies a BACH2-NRF2 axis regulating fetal hemoglobin activation through genetic and functional analyses in a large multi-ancestry cohort.

This paper develops a multi-omic framework to predict human immune responses from mouse models across various stimuli, finding that functional modules are more conserved than individual genes.

The paper identifies multiple CDV spillover events into Neotropical primates in Brazil and identifies residue 519 of the hemagglutinin protein as a candidate marker of adaptation to primates.

This study identifies FDXR upregulation as a prognostic marker and therapeutic target in HTLV-1-associated ATL, showing its link to disease severity and sensitivity to fluorouracil.

The study detects Trypanosoma sp. in Streblidae flies parasitizing bats using shotgun metagenomics, expanding knowledge of Neobat 4 clade distribution.

The paper analyzes DENV-1 genome sequences from Araraquara, Brazil, to reconstruct its evolutionary history and challenge previous assumptions about the emergence of genotype V.

This study identifies 59 sentinel variants and two novel genes associated with telomere length using whole genome sequences from 109,122 trans-ethnic individuals.

The paper develops an automated pyrosequencing technique to confirm sickle cell disease and detect HBB gene mutations, showing high accuracy in identifying hemoglobin variants.

The paper examines HERV-K and HERV-W transcriptional activity in ME/CFS patients, finding HERV-K overexpression in moderately affected individuals.

The paper identifies germline genetic variants associated with clonal hematopoiesis of indeterminate potential (CHIP) using whole genome sequences from the TOPMed program.

This study identifies a new DENV2 lineage replacement in Brazil using portable genomic surveillance, detecting its introduction from the Caribbean in 2014.

This paper describes a method to sequence Zika and other virus genomes directly from clinical samples using multiplex PCR and portable sequencing technologies, achieving complete genomes in 1-2 days.

The paper uses ZIKV genomes to estimate the origin and spread of Zika virus in Brazil and the Americas, providing a timeframe for baseline microcephaly rates.