Author

Ebenezer N. Yamoah

University of Nevada, RenoORCID 0000-0002-9797-085XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Assay:electronic health records· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bernd FritzschiD· 2 shared Jinsil Choi· 2 shared Seojin ParkiD· 2 shared Yingying CheniD· 2 shared Braulio PegueroiD· 1 shared Carrie J. FinnoiD· 1 shared Eric VerschooteniD· 1 shared Fan ZhangiD· 1 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Bernd FritzschORCID

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Author profile →

5 papers

Recent·Most cited

Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

Yingying Chen, Jeong Han Lee, Jin Li, Seojin Park, Maria Cristina Perez Flores, Braulio Peguero, Jennifer Kersigo, Mincheol Kang, Jinsil Choi, Lauren Levine, Michael Anne Gratton, Bernd Fritzsch, Ebenezer N. Yamoah

This study shows reducing Cldn9 levels pharmacogenetically generates functional inner hair cells in mice, which are durable and resemble normal cells.

bioRxiv · Oct 8, 2023 · PreprintNeuroscience

Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through Kv7.4 channel upsurge in auditory neurons and hair cells

Haiwei Zhang, Hongchen Li, Mingshun Lu, Shengnan Wang, Xueya Ma, Fei Wang, Jiaxi Liu, Xinyu Li, Haichao Yang, Fan Zhang, Haitao Shen, Noel J. Buckley, Nikita L. Gamper, Ebenezer N. Yamoah, Ping Lv

This study shows that REST deficiency leads to increased Kv7.4 channels in auditory neurons and hair cells, causing progressive hearing loss, which can be reversed by Kv7.4 inhibition.

eLife · Sep 20, 2022Peer-reviewedNeuroscience

ISL1 is necessary for auditory neuron development and contributes towards tonotopic organization

Iva Filová, Kateryna Pysanenko, Mitra Tavakoli, Simona Vochyánová, Martina Dvořáková, Romana Bohuslavová, Ondřej Smolík, Valeria Fabriciova, Petra Hrabalova, Sarka Benesova, Lukáš Valihrach, Jiri Cerny, Ebenezer N. Yamoah, Josef Syka, Bernd Fritzsch, Gabriela Pavlínková

This study shows that ISL1 is essential for auditory neuron development and tonotopic organization, but central plasticity cannot fully compensate for peripheral dysfunction.

Proceedings of the National Academy of Sciences · Sep 8, 2022Peer-reviewedNeuroscience

Cisplatin neurotoxicity targets specific subpopulations and K+ channels in tyrosine-hydroxylase positive dorsal root ganglia neurons

Carrie J. Finno, Yingying Chen, Seojin Park, Jeong Han Lee, Maria Cristina Perez-Flores, Jinsil Choi, Ebenezer N. Yamoah

This study identifies cisplatin's effect on specific subpopulations of TH+ DRGNs and shows K+ channel involvement in neurotoxicity.

Frontiers in Cellular Neuroscience · May 2, 2022Peer-reviewedNeuroscience

Intrinsic mechanical sensitivity of auditory neurons as a contributor to sound-driven neural activity

Maria C. Perez Flores, Eric Verschooten, Jeong Han Lee, Hyo Jeong Kim, Philip X. Joris, Ebenezer N. Yamoah

This study investigates how mechanical sensitivity in auditory neurons contributes to sound-driven neural activity by shaping phase-locked responses and frequency tuning.

eLife · Mar 10, 2022Peer-reviewedNeuroscience