Author

Clare W. Cahir

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-2677-199XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Cameron G. RobertsiD· 1 shared Christian Fredrick BacaiD· 1 shared Dinshaw J. PateliD· 1 shared Héloïse Carion· 1 shared Luciano A. MarraffiniiD· 1 shared Puja MajumderiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Cameron G. RobertsORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintNov 13, 2025

Cyclic tetra-adenylate triggers Cap1 membrane pore opening and depolarization during the type III CRISPR immune response

Puja Majumder, Clare W. Cahir, Christian Fredrick Baca…·Luciano A. Marraffini

This study reveals how cyclic tetra-adenylate binds to Cap1, inducing conformational changes that open a membrane pore and cause depolarization during the type III CRISPR immune response.

DOI 10.1101/2025.11.13.688252

structural biologyexperimental assay

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