MicrobiologybioRxivPreprint
A lipid fenestration-gated membrane depolarization mechanism expands the repertoire of CRISPR-mediated anti-phage defense strategies
Puja Majumder, Héloïse Carion, Gianna Stella…·Luciano A. Marraffini
The paper identifies a lipid-gated mechanism in CRISPR-Cas systems that uses membrane depolarization to block viral replication.
DOI 10.64898/2026.08.05.743128