Author

Héloïse Carion

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Luciano A. MarraffiniiD· 3 shared Dinshaw J. PateliD· 2 shared Puja MajumderiD· 2 shared Alice K. CasseliD· 1 shared Cameron G. RobertsiD· 1 shared Christian Fredrick BacaiD· 1 shared Clare W. CahiriD· 1 shared Gianna StellaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

Luciano A. MarraffiniORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 6, 2026

A lipid fenestration-gated membrane depolarization mechanism expands the repertoire of CRISPR-mediated anti-phage defense strategies

Puja Majumder, Héloïse Carion, Gianna Stella…·Luciano A. Marraffini

The paper identifies a lipid-gated mechanism in CRISPR-Cas systems that uses membrane depolarization to block viral replication.

DOI 10.64898/2026.08.05.743128

bacteria (other)proteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintMay 9, 2026

Mre11-Rad50 enhances spacer acquisition in a haloarchaeal Type I-B CRISPR-Cas system

Alice K. Cassel, Héloïse Carion, Luciano A. Marraffini

This study shows that Mre11-Rad50 enhances spacer acquisition in a haloarchaeal Type I-B CRISPR-Cas system, while Fen1 does not play a significant role.

DOI 10.64898/2026.05.08.723854

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

MicrobiologybioRxivPreprintNov 13, 2025

Cyclic tetra-adenylate triggers Cap1 membrane pore opening and depolarization during the type III CRISPR immune response

Puja Majumder, Clare W. Cahir, Christian Fredrick Baca…·Luciano A. Marraffini

This study reveals how cyclic tetra-adenylate binds to Cap1, inducing conformational changes that open a membrane pore and cause depolarization during the type III CRISPR immune response.

DOI 10.1101/2025.11.13.688252

structural biologyexperimental assay

𝕏 PostBluesky