Ying Yi Zheng

This study develops 2D and 3D human in vitro neurovascular unit models to investigate microglial interactions with endothelial cells and their role in neurovascular function under inflammatory conditions.

This paper develops a 3D human brain endothelial platform combined with machine learning to identify kinase inhibitors that restore blood-brain barrier integrity in TBI.

This study examines how shear stress and pressure affect pulmonary arterial endothelial cells in health and PAH, revealing divergent transcriptional responses across disease states and donor sex.

CAR T cell therapy causes cytokine release, leading to increased endothelial-leukocyte interactions and brain capillary plugging, which correlates with neurotoxicity.

This study investigates how hydrostatic pressure modulates endothelial cell responses to flow, showing pressure alters shear-induced signaling and transcriptional changes in human and mouse ECs.