Author

Yu Jung Shin

Johns Hopkins UniversityORCID 0000-0002-7429-289XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Albert Park· 1 shared Alexis KaushanskyiD· 1 shared C. Na· 1 shared Christina Ren· 1 shared Devanik BiswasiD· 1 shared Hao Wen CheniD· 1 shared Harry Higgins· 1 shared Hyejin ParkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Albert Park

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2 papers

Recent·Most cited

Reactive Astrocytes Drive Extracellular Acidification to Mediate α-Synuclein Neurodegeneration

Jae‐Jin Song, Hyejin Park, YuRee Choi, Taekyung Ryu, Jisu Shin, Seo-Hyun Kim, Albert Park, Justin Wang, Devanik Biswas, Shih-Ching Chou, Shinwon Ha, Yura Jang, Yu Jung Shin, Hao Wen Chen, Ingie Hong, , Tae‐In Kam

This study identifies a mechanism by which reactive astrocytes drive neurodegeneration in synucleinopathies through extracellular acidification and neuronal ASIC1a activation.

bioRxiv · Mar 4, 2026 · PreprintNeuroscience

A Machine Learning- 3D Microvessel Platform Identifies Kinase Targets Restoring Blood-Brain-Barrier Endothelial Integrity.

Yu Jung Shin, Ling Wei, Sumin Hong, Christina Ren, M. Zigman Jeffrey, Jessica Cardenas, Harry Higgins, Nhi Ho, Kira M. Evitts, Joseph D. Smith, Jing‐fei Dong, Alexis Kaushansky, Ying Yi Zheng

This paper develops a 3D human brain endothelial platform combined with machine learning to identify kinase inhibitors that restore blood-brain barrier integrity in TBI.

bioRxiv · Dec 15, 2025 · PreprintBioengineering