Sandhya Srikant Visweswariah

This study shows that aged mice have increased susceptibility to Citrobacter rodentium infection but retain distinct molecular and inflammatory responses depending on the pathogen's virulence.

This study shows that Drosophila hemocytes use Upd3 to signal the gut after injury, maintaining intestinal homeostasis and survival.

This study shows GBP1 is recruited to actin-rich pedestals formed by extracellular pathogens, promoting pyroptosis and IL-18 release, independent of LPS.

The paper identifies two coevolving residues distant from the ligand binding site in GAF domains that are critical for allostery, using computational and experimental methods.

This study identifies a conserved metallophosphodiesterase in Drosophila that influences lifespan, with neuronal expression capable of rescuing lifespan defects.