Tagari Samanta

This paper shows that Tamoxifen and Doxorubicin together target the ER beta-mutant p53-p73 axis in TNBC, enhancing cell death through apoptosis and ferroptosis.

This study identifies TAK1 as a key regulator of oncogenic signaling and differentiation blockade in rhabdomyosarcoma, showing its role in promoting proliferation and inhibiting myogenic differentiation.

The paper develops a mathematical model to explain how glucose regulates Nanog expression and drives differential proliferation in cancer stem cells through STAT3 and p53 dynamics.

This study shows how altering microRNA regulation can control Nanog expression heterogeneity in ESCs to guide cell-type specific differentiation.

The paper models Nanog expression heterogeneity in ESCs using a stochastic simulation to show how culture conditions affect transcriptional noise partitioning.