Author

Shixia Huang

Baylor College of MedicineORCID 0000-0003-2878-4129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Yi LiiD· 2 shared Yongchao DouiD· 2 shared Alanna Jean WattiD· 1 shared Alexandria Z. BuiD· 1 shared Amy Tsu KuiD· 1 shared Anna A. CookiD· 1 shared Arun SreekumariD· 1 shared Bart O. WilliamsiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Yi LiORCID

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3 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJun 22, 2026

Rat somatic genome editing enables ER+ breast cancer modeling

Wen Bu, Tobie D. Lee, Meenakshi Anurag…·Yi Li

This study enables efficient somatic genome editing in rats to model ER+ breast cancer, showing that rat tumors recapitulate key features of human ER+ breast cancer not observed in mice.

DOI 10.1073/pnas.2529653123

ratexperimental assay

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Cancer BiologybioRxivJan 10, 2024

Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

Fei Yue, Amy Tsu Ku, Payton D. Stevens…·Yi Li

The paper shows that ZNRF3/RNF43 ubiquitinates and degrades EGFR, and their loss increases EGFR signaling, promoting cancer growth.

3 citations

humanproteomics

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NeuroscienceScience AdvancesPeer-reviewedSep 16, 2022

Restoration of BDNF-TrkB signaling rescues deficits in a mouse model of SCA6

Anna A. Cook, Sriram Jayabal, Jacky Sheng…·Alanna Jean Watt

This study shows that restoring BDNF-TrkB signaling through exercise or a BDNF mimetic improves motor coordination and cerebellar function in a mouse model of SCA6.

32 citations

mouseexperimental assay

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