Mario Abdelmessih

The paper identifies codon pairs and amino acid pairs as regulators of mRNA stability in zebrafish, showing context-dependent decay mechanisms involving deadenylation and decapping.

The paper introduces a normalization method for DNA-encoded library selections using antibody fragments and DNA-conjugated peptides to improve accuracy and reduce noise in data analysis.

This paper introduces a method to improve protein-protein interaction prediction by using topology-driven negative sampling and an ML pipeline that enhances generalizability and interpretability.

The paper investigates the developmental fate of zebrafish embryos lacking the reprogramming factors Nanog, Pou5f3, and Sox19b, finding that cells can acquire novel cell states or primordial germ cell-like states.

The paper identifies cis-regulatory elements and trans-factors governing mRNA stability during zebrafish MZT and develops a model to predict mRNA stability.